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Treatment By Stage
Breast cancer treatment depends on
the type and stage of the disease, and the patient's age, menopausal
status, and overall health.
Standard treatment may be considered
because of its effectiveness in patients in past studies, or
participation in a clinical trial may be considered. Not all patients
are cured with standard therapy and some standard breast cancer treatments may have
more side effects than are desired. For these reasons, clinical trials
are designed to find better ways to treat cancer patients and are based
on the most up-to-date information. Clinical trials are ongoing in most
parts of the country for all stages of breast cancer. To learn more
about clinical trials, call the Cancer Information Service at
1-800-4-CANCER (1-800-422-6237); TTY at 1-800-332-8615.
Ductal Carcinoma In Situ
If the patient has ductal carcinoma in
situ (DCIS), treatment may be one of the following:
- Breast-conserving surgery with
radiation therapy, with or without hormone therapy.
- Surgery to remove the whole breast
(total mastectomy), with or without hormone therapy.
- Clinical trials comparing
breast-conserving surgery and hormone therapy with or without
radiation therapy.
Lobular Carcinoma In Situ
If the patient has lobular carcinoma in
situ (LCIS), treatment may be one of the following:
- Biopsy to diagnose the LCIS
followed by regular examinations and regular mammograms to find any
changes as early as possible.
- Hormone therapy to reduce the risk
of developing breast cancer.
- Clinical trials including a large
clinical trial (Study of Tamoxifen and Raloxifene--STAR
trial)comparing 2 types of hormone therapy to lower the risk of
developing breast cancer and to compare the side effects of
treatment. The Cancer Information Service can be called for more
information (1-800-4-CANCER).
- Surgery to remove all of both
breasts (total bilateral mastectomy). This treatment choice is
sometimes used in women who have a high risk of getting breast
cancer. Most surgeons believe that this is a more aggressive
treatment than is needed.
Stage I, II, and IIIA Breast Cancer
Primary treatment may be one of the
following:
- If the cancer is confined to the
breast and lymph nodes under the arm:
- Breast-conserving surgery to
remove only the cancer and some surrounding breast tissue
(lumpectomy) followed by radiation therapy. Some of the lymph
nodes under the arm are also removed.
- Surgery to remove the whole
breast and the lining over the chest muscles (modified radical
mastectomy), as well as some of the lymph nodes under the arm
with or without breast reconstruction surgery.
- A clinical trial evaluating
limited lymph node removal (sentinel lymph node biopsy).
Adjuvant therapy (given in
addition to the treatments listed above) may include:
- Radiation therapy to the lymph
nodes under the arm following a modified radical mastectomy.
- Systemic chemotherapy with or
without hormone therapy.
Stage IIIB, IV, Recurrent, and
Metastatic Breast Cancer
Treatment for breast cancer that comes
back (recurs) to the breast or chest wall may include:
- Surgery (radical or modified
radical mastectomy) and/or radiation therapy.
- Systemic chemotherapy or hormone
therapy.
Treatment for Stage IIIB cancer or
inflammatory breast cancer may include one or more of the following:
- Systemic chemotherapy.
- Systemic chemotherapy followed by
surgery (breast-conserving surgery or total mastectomy) with lymph
node removal followed by radiation therapy. Additional systemic
therapy (chemotherapy and/or hormone therapy) may be given).
- Clinical trials testing new
chemotherapy drugs, new drug combinations, and new ways of giving
treatment.
Treatment for Stage IV cancer or
metastatic breast cancer may include one or more of the following:
- Hormone therapy and/or
chemotherapy with or without trastruzumab (Herceptin).
- Radiation therapy and/or surgery
to relieve the pain caused by the cancer.
- Clinical trials testing new
chemotherapy and/or hormone therapy. Clinical trials are also
studying new combinations of trastruzumab (Herceptin) with
chemotherapy drugs.
- Clinical trials evaluating other
approaches, including high-dose chemotherapy with bone marrow or
peripheral stem cell transplantation.
To Learn More
For more information, call the National
Cancer Institute's Cancer Information Service at 1-800-4-CANCER
(1-800-422-6237); TTY at 1-800-332-8615. The call is free and a trained
information specialist is available to answer your questions.
The National Cancer Institute has
booklets and other materials for patients, health professionals, and the
public. These publications discuss types of cancer, methods of cancer
treatment, coping with cancer, and clinical trials. Some publications
provide information on tests for cancer, cancer causes and prevention,
cancer statistics, and NCI research activities. NCI materials on these
and other topics may be ordered online from the NCI Publications Locator
Service at
http://publications.nci.nih.gov or by telephone from the Cancer
Information Service toll free at 1-800-4-CANCER.
There are many other places where
people can get materials and information about cancer treatment and
services. Local hospitals may have information on local and regional
agencies that offer information about finances, getting to and from
treatment, receiving care at home, and dealing with problems associated
with cancer treatment. A list of organizations and websites that offer
information and services for cancer patients and their families is
available on CancerNet at
http://cancernet.nci.nih.gov/cancerlinks.html.
For more information from the National
Cancer Institute, please write to this address:
- National Cancer Institute
Office of Cancer Communications
31 Center Drive, MSC 2580
Bethesda, MD 20892-2580
Adapted from information provided by
The National Cancer Institute. |
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